Brumley Dissertation_Synthetic Organic Chemistry. Below are a list of required tasks for my dissertation document. In general the document is a mix of synthetic chemistry and biology. Chapters 1-2 are based on 3 peer reviewed American Chemical society publications.
Topic: Brumley Dissertation — Synthetic Organic Chemistry
Paper details: Below are a list of required tasks for my dissertation document. In general the document is a mix of synthetic chemistry and biology. Chapters 1-2 are based on 3 peer reviewed American Chemical society publications. Chapter 3 Contains unpublished data.
In general I have 2-3 source word documents containing the material that needs to be compiled into the university template.
The tasks required will include:
1) Moving chemical structures and NMR data from a preexisting word document into the University template.
2) Numbering of Chemical structures based on the university conventions. These numbers appear under each compound — a chemist will understand this. I
can handle the citing of compounds within the text — I just need them numbered appropriately. The university policy is that the 3rd compound in chapter 1 will
appear as 1.3, the 8th compound in chapter 3 will be 3.8 etc.
3) General formatting of the document based on the university standard. This will include citations, data appendix etc.
The traditional (and still prevalent) way to teach organic chemistry is to focus on examples that are primarily of interest to students who are planning to become professional organic chemists – that is, to focus on the molecules and reactions of organic synthesis, considering mainly non-aqueous conditions and non-biological reagents.
The majority of students studying organic chemistry, however, are doing so because they are majoring in biology, biochemistry, or health sciences. They need to learn about the structure and reactivity of organic compounds because, quite simply, organic chemistry is the chemistry of life. What is most interesting and relevant to these students is the organic chemistry that takes place in the context of a living cell.
In this online textbook, a unique approach is taken to the study of organic chemistry. To the greatest extent possible, biological molecules and biochemical reactions are used to explain and illustrate the central concepts of organic chemistry. This novel approach is most evident in chapters 9-17, which cover the main organic reaction mechanisms in a biological context.
However, earlier chapters on organic structure and spectroscopy also focus as much as possible on examples of interest to students of biology and the health sciences. The chemistry of lab synthesis is not ignored – however, these examples are generally grouped together in subsections and introduced to illustrate parallels between laboratory and biological chemistry.
The traditional approach to teaching Organic Chemistry, taken by most of the textbooks that are currently available, is to focus primarily on the reactions of laboratory synthesis, with much less discussion – in the central chapters, at least – of biological molecules and reactions.
This is despite the fact that, in many classrooms, a majority of students are majoring in Biology or Health Sciences rather than in Chemistry, and are presumably taking the course in order to learn about the chemistry that takes place in living things.
In an effort to address this disconnect, I have developed a textbook for a two-semester, sophomore-level course in Organic Chemistry in which biological chemistry takes center stage. For the most part, the text covers the core concepts of organic structure, structure determination, and reactivity in the standard order.
What is different is the context: biological chemistry is fully integrated into the explanation of central principles, and as much as possible the in-chapter and end-of-chapter problems are taken from the biochemical literature. Many laboratory synthesis reactions are also covered, generally in parallel with their biochemical counterparts – but it is intentionally the biological chemistry that comes first.